Mustafa (Safa) Karagöz-Postdoctoral Researcher
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Experience
Postdoctoral Researcher
National Institutes of Health (NIH), NHLBI
- Led peptide inhibitor design against UPF1 using RFdiffusion, ProteinMPNN, and AlphaFold2/3; validated candidates with molecular dynamics simulations
- Screened over 1 million compounds for ataxia fusion proteins via AutoDock Vina; confirmed top hits using GROMACS MD simulations
- Developed RNA-seq analysis pipelines for nonsense-mediated decay (NMD) studies including isoform quantification and motif discovery
- Modeled protein-RNA interactions using AlphaFold3 multimers integrated with BioGRID/STRING databases
- Established computational workflows for transcriptomics and RNA regulation in iPSC-derived human models
PhD Researcher
Technische Universität Braunschweig
- Investigated Legionella pneumophila virulence factors integrating structural biology and interactomics approaches
- Utilized AlphaFold and Rosetta for modeling pathogen-host interactions; identified druggable targets for therapeutic intervention
- Purified effector proteins and validated ligand binding using nanoDSF and surface plasmon resonance (SPR)
- Applied human lung explants to connect molecular mechanisms with tissue-level responses to infection
- Integrated AP-MS proteomics data with computational modeling to map host-pathogen interaction networks
Research Assistant
Türkisch-Deutsche Universität
- Developed computational models for amyloid formation and disordered protein behavior
- Designed peptide and protein variants using homology modeling, molecular docking, and high-performance computing
- Established molecular modeling workflows for protein structure-function analysis
Project Assistant
TÜBİTAK Marmara Technopark (MARTEK)
- Performed pharmacological assays and biosensor studies for preclinical drug testing
- Supported automation-based in vivo and ex vivo drug validation protocols
Research Intern
Instituto Gulbenkian de Ciência (IGC)
- Conducted pharmacological assays and in vivo studies on therapeutic candidates
- Contributed to synthetic biology and high-throughput screening pipelines
Research Intern
Bogazici University
- Performed molecular biology assays for drug testing and validation
Industry experience
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Experienced in Biotechnology, Pharmaceutical, and Education.
Business area experience
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Experienced in Research and Development.
Summary
Computational biologist with 8+ years of experience bridging experimental biology and computational innovation. Expertise in protein design, structural bioinformatics, and transcriptomics applied to therapeutic discovery. Successfully led projects from molecular modeling to validation in human model systems. Proven ability to integrate multi-omics data, develop computational pipelines, and translate findings into biological insights for undruggable targets.
Skills
Protein Design
- Alphafold2/3
- Rfdiffusion
- Proteinmpnn
- Rosetta Suite
Structural Biology
- Molecular Dynamics
- Pymol/Chimerax
- Gromacs
Computational Methods
- Python/R Programming
- Hpc/Cloud Computing
- Bioinformatics Pipelines
- Bash Scripting
Transcriptomics
- Rna-Seq Analysis
- Isoform Quantification
- Motif Discovery
- Nmd Studies
Experimental Techniques
- Protein Purification
- Nanodsf/Spr
- Mass Spectrometry
- Mammalian/Ipsc Culture
Specialized Knowledge
- Host-Pathogen Interactions
- Drug Discovery Pipelines
- Multi-Omics Integration
- Undruggable Targets
Technical Skills
- Protein Design: Alphafold2/3, Rfdiffusion, Proteinmpnn, Rosetta
- Structural Analysis: Pymol, Chimerax, Gromacs, Autodock Vina
- Transcriptomics: Rna-Seq, Isoform Quantification, Motif Discovery
- Programming: Python, R, Bash Scripting
- Computational: Hpc, Cloud Computing, Bioinformatics Pipelines
Languages
Education
Technische Universität Braunschweig
PhD in Biology, Protein interaction and inhibition of L. pneumophila Mip and immunometabolism · Biology · Braunschweig, Germany
Gebze Technical University
M.Sc. Molecular Biology & Genetics, Molecular characterization and identification of the interaction partner of the peptidyl · Molecular Biology & Genetics · Turkey
Gebze Technical University
B.Sc. Molecular Biology & Genetics · Molecular Biology & Genetics · Turkey
Statistics
Experience
Global experience
Expertise
Qualifications
Profile
Frequently asked questions
Have questions? Find more information here.
Mustafa is based in Detmold, Germany.
Mustafa speaks the following languages: German (Native), Turkish (Native), English (Advanced).
Mustafa has at least 9 years of experience. During this time, Mustafa has worked in at least 5 different roles and for 6 different companies. The average length of individual experience is 2 years and 6 months. Note that Mustafa may not have shared all experience and actually has more experience.
Based on recent experience, Mustafa would be well-suited for roles such as: Postdoctoral Researcher, PhD Researcher, Research Assistant.
Mustafa's most recent position is Postdoctoral Researcher at National Institutes of Health (NIH), NHLBI.
In recent years, Mustafa has worked for National Institutes of Health (NIH), NHLBI and Technische Universität Braunschweig.
Mustafa is most experienced in industries like Biotechnology, Pharmaceutical, and Education.
Mustafa is most experienced in business areas like Research and Development.
Mustafa has recently worked in industries like Biotechnology and Pharmaceutical.
Mustafa has recently worked in business areas like Research and Development.
Mustafa holds a Doctorate in Biology from Technische Universität Braunschweig, a Master in Molecular Biology & Genetics from Gebze Technical University and a Bachelor in Molecular Biology & Genetics from Gebze Technical University.
The availability of Mustafa needs to be confirmed.
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Calculated based on our freelancers’ daily rates as of 7 Sep 2026. Actual rates may vary depending on seniority level, experience, skill specialization, project complexity, and engagement length.
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