Recommended expert
Ziming Huang
Research Scientist
Experience
Sep 2022 - Present
3 years 7 monthsMunich, Germany
Research Scientist
LMU Klinikum and Helmholtz München
Position Summary
Research Scientist at LMU Klinikum and Helmholtz München
Industries
Biotechnology
Healthcare
Business Areas
Research and Development
- Spearheaded collaborative research projects in cardiovascular immunology, utilizing scRNA-seq analysis to elucidate the molecular mechanisms of complement component 5a signaling in innate immune macrophages
- Drove the discovery and validation of novel genes and pathways in cardiomyopathies by integrating complex clinical and real-world datasets (e.g., SNP genotyping, electronic medical records)
- Engineered a novel 1DCNN-Transformer hybrid architecture for miRNA-mRNA binding prediction directly from DNA sequences achieving SOTA performance with a superior AUC of 0.903 that significantly reduced false-positive rates compared to benchmark models, released on [link]
Mar 2021 - Jun 2021
4 monthsAI Scientist
Kaggle Competition – Molecular Translation
Position Summary
AI Scientist at Kaggle Competition – Molecular Translation
Industries
Chemical
Pharmaceutical
Business Areas
Information Technology
Research and Development
- Led a 4-person team to achieve 2nd place among 874 competitors (Kaggle Grandmaster Top 0.1%) in the Molecular Translation Challenge, successfully solving the critical data transformation challenge of low OCR accuracy on a large, corrupted FDA-sourced chemical molecular scanned image dataset
- Engineered a 3-phase model featuring ResNet-Transformer image captioning, candidate generation, and multi-model re-ranking
- Boosted model robustness by 40% through molecular-specific data augmentation, achieving an Edit Distance of 0.54 (vs. baseline 0.9+), and enabling accurate conversion of 1.6 million legacy chemical scanned images into machine-readable InChI format
Mar 2019 - Jun 2022
3 years 4 monthsShanghai, China
Research Scientist
Shanghai Institute of Materia Medica
Position Summary
Research Scientist at Shanghai Institute of Materia Medica
Industries
Biotechnology
Pharmaceutical
Business Areas
Research and Development
- Resolved API integration codes for models like GPT-3.5-turbo in chemical text-mining tasks, and designed batch data transfer strategies to support large-scale chemical literature processing
- Conducted structure-based virtual screening to identify potential inhibitors targeting the interaction between SARS-CoV-2 spike protein receptor-binding domain and host cell angiotensin-converting enzyme 2, which is a key step in viral entry into host cells
- Engineered and validated a Random Forest model for Immune Checkpoint Inhibitor (ICI) response prediction using multi-omics data from 281 cancer patients, achieving a state-of-the-art AUC of 0.85 on external validation, significantly surpassing the baseline model (AUC, 0.763), and identifying novel biomarkers enriched in crucial immune pathways
Nov 2017 - Jun 2018
8 monthsQingdao, China
Intern
BGI Genomics
Position Summary
Intern at BGI Genomics
Industries
Biotechnology
Business Areas
Research and Development
- Engineered a bit-parallel fuzzy regex pipeline to perform SNP-tolerant cross-species comparative genomics on five Takifugu species, enabling automated annotation of conserved genomic sites
- Achieved a 10-time speedup in querying and accessing 30 GB of genome annotation data using a MySQL database (python library), significantly improving the efficiency of comparative analysis
- Based on above results, automated the entire RNA-Seq analysis pipeline in Linux, from read mapping and data cleaning to gene annotation, standardizing the workflow for high-throughput data processing
Jun 2016 - Sep 2016
4 monthsWuhan, China
Data Scientist
National Mathematical Modeling Competition
Position Summary
Data Scientist at National Mathematical Modeling Competition
Industries
Biotechnology
Business Areas
Research and Development
- Achieved the National second Prize (among Graduates) in the competition, served as lead model developer and scientific writer
- Developed and applied a Logistic Regression model combined with GWAS statistical testing on 9445 SNPs to accurately identify the three most likely disease-associated loci for the target-inherited disease within 300 provided genes
Industry Experience
See where this freelancer has spent most of their professional time.
Experienced in Biotechnology, Healthcare, Pharmaceutical, and Chemical.
Biotechnology
Healthcare
Pharmaceutical
Chemical
Business Area Experience
See which departments and functions this freelancer has contributed to most.
Experienced in Research and Development and Information Technology.
Research and Development
Information Technology
Skills
- Programming: Python, Pandas, Scikit-learn, Pytorch, Pysql, R, Sas, Git, Jupyter, Vscode, Google Colab
- Life Science: Oncology Research, Cardiology Clinical Research, Immunology, Genetics, Molecular Biology, Cell Biology
- Informatics: Statistics, Mathematical Modeling, Ml&dl, Bayesian Network, Transformer, High Performance Computing (Hpc)
- Bioinformatics/cheminformatics: Scrna-seq Analysis, Rna-seq Analysis, Gwas, Quantitative Structure-activity Relationship (Qsar)
- Scientific: Research Project Management, Academic Writing, Teamwork
Languages
Chinese
NativeEnglish
AdvancedGerman
ElementaryEducation
Sep 2022 - Present
Ludwig-Maximilians-Universität München
PhD candidate in Medical Research · Medical Research · Munich, Germany
Sep 2019 - Jun 2022
University of Chinese Academy of Sciences
Master of Science in AI-assisted Drug Design · AI-assisted Drug Design · China
Sep 2014 - Jun 2018
Huazhong Agricultural University
Bachelor of Science in Bioinformatics · Bioinformatics · Wuhan, China
Statistics
Experience
Total positions 5
Experience in Biotechnology 7.5 y
Avg length 1 y 7 m
Longest experience 3 y 6 m
Global Experience
Countries worked in 2 (China, Germany)
Primary country China
Expertise
Recent roles Research Scientist, AI Scientist, Intern
Main industries Biotechnology, Healthcare, Pharmaceutical
Main business areas Research and Development, Information Technology
Qualifications
Highest degree Doctorate
Profile
Created
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Frequently asked questions
Do you have questions? Here you can find further information.
Where is Ziming based?
Ziming is based in Munich, Germany.
What languages does Ziming speak?
Ziming speaks the following languages: Chinese (Native), English (Advanced), German (Elementary).
How many years of experience does Ziming have?
Ziming has at least 8 years of experience. During this time, Ziming has worked in at least 4 different roles and for 5 different companies. The average length of individual experience is 2 years and 6 months. Note that Ziming may not have shared all experience and actually has more experience.
What roles would Ziming be best suited for?
Based on recent experience, Ziming would be well-suited for roles such as: Research Scientist, AI Scientist, Intern.
What is Ziming's latest experience?
Ziming's most recent position is Research Scientist at LMU Klinikum and Helmholtz München.
What companies has Ziming worked for in recent years?
In recent years, Ziming has worked for LMU Klinikum and Helmholtz München, Kaggle Competition – Molecular Translation, and Shanghai Institute of Materia Medica.
Which industries is Ziming most experienced in?
Ziming is most experienced in industries like Biotechnology, Healthcare, and Pharmaceutical. Ziming also has some experience in Chemical.
Which business areas is Ziming most experienced in?
Ziming is most experienced in business areas like Research and Development and Information Technology.
Which industries has Ziming worked in recently?
Ziming has recently worked in industries like Biotechnology, Healthcare, and Pharmaceutical.
Which business areas has Ziming worked in recently?
Ziming has recently worked in business areas like Research and Development and Information Technology.
What is Ziming's education?
Ziming holds a Doctorate in Medical Research from Ludwig-Maximilians-Universität München, a Master in AI-assisted Drug Design from University of Chinese Academy of Sciences and a Bachelor in Bioinformatics from Huazhong Agricultural University.
What is the availability of Ziming?
Ziming is immediately available full-time for suitable projects.
What is the rate of Ziming?
Ziming's rate depends on the specific project requirements. Please use the Meet button on the profile to schedule a meeting and discuss the details.
How to hire Ziming?
To hire Ziming, click the Meet button on the profile to request a meeting and discuss your project needs.
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Market avg: 830-990 €
Market avg: 830-990 €
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