Sandeep Kesh-Postdoctoral Researcher
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Experience
Postdoctoral Researcher
Friedrich Schiller University
- Established and optimized viral detection assays (SARS-CoV-2, IAV) in A549 and Vero cell lines using qPCR, immunofluorescence and AFM-based morphology analysis to generate quantitative data on viral protein expression and particle quality
- Characterized protein aggregation and fibril formation using NanoFTIR, fluorescence spectroscopy, Raman and ThT assays, linking biophysical signatures to stability and quality attributes of protein formulations
- Applied statistics-based data analysis to evaluate assay robustness and variability, supporting QbD-oriented discussions on method performance and critical analytical parameters
- Led method development and data interpretation for analytical workflows, collaborating with cross-functional colleagues and training team members on advanced biophysical instrumentation
Scientific Assistant (PhD Scholar)
University Hospital Jena
- Designed and executed robustness studies for cell-based ion channel assays by systematically varying key parameters (cell density, incubation time, cRNA concentration), defining design space and acceptable operating ranges, resulting in comprehensive SOP documentation and enhanced assay reliability
- Led product characterization and screening of small molecules, RNA, and DNA targeting CNG ion channels using HPLC, UV-Vis, fluorescence spectroscopy, and DLS, generating integrated datasets on purity, aggregation, and functional activity that informed critical quality attribute (CQA) evaluations
- Developed and optimized analytical protocols for RNA and protein quality and stability by implementing rigorous validation steps, supporting preclinical drug development and ensuring accurate assessment of product-related quality attributes
Research Assistant
University of Iowa
- Developed, synthesized and optimized nanoparticle-based drug formulations using electrophoretic methods, DLS and SLS to characterize particle size, charge and stability, and subsequently optimized formulations for lyophilization for in vivo mouse studies in cystic fibrosis
- Designed and evaluated the stability of ubiquinol/gamma-cyclodextrin formulations using Turbiscan, ROS and MTS assays, flow cytometry and DLS, linking analytical results to formulation performance and product quality
Deputy Manager
Development Alternatives
- Managed a microbiology lab in a cGMP manufacturing environment, implementing safety protocols and SOPs for pilot testing of a rapid bacterial detection kit, ensuring compliant documentation and contributing to method validation reports
- Performed material characterization (XRD, PSD, ITC) to define key material properties, feeding analytical results into risk assessments and formulation decisions for industrial applications
Research Internship
National Chemical Laboratory, Pune
- Conducted a multi-spectroscopic investigation integrating IR, UV-Vis, ¹³C NMR and molecular dynamics simulations to quantify interactions between BSA and testosterone (protein-ligand interactions)
Master Thesis Student
National Institute of Technology, Rourkela
- Characterized protein-ligand (Lysozyme and Rhodamine B) interactions using biophysical techniques (UV-Vis, fluorescence, CD, molecular docking) to characterize changes in secondary structures
Industry experience
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Experienced in Biotechnology, Pharmaceutical, Healthcare, and Chemical.
Business area experience
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Experienced in Research and Development, Quality Assurance, and Product Development.
Summary
Scientist with 6+ years’ experience in analytical development and process characterization for biologics and complex formulations, including robustness studies, product characterization and method validation. Hands-on background with chromatographic and spectroscopic methods (HPLC, UV-Vis, fluorescence, DLS, ITC, AFM) and biological assays (ELISA, Nanoluciferase, cell-based assays). Practical exposure to Quality-by-Design concepts and risk-based thinking, now aiming to contribute as a Product Expert / Analytical Process Manager, driving CQA evaluation and QbD-based analytical strategies in biopharmaceutical projects.
Skills
- Molecular Biology
- Chromatographic (Hplc)
- Protein Purification
- Rna/Dna Extraction
- Qpcr
- Spectroscopic Techniques
- Uv-Vis
- Fluorescence
- Lc-Ms
- Electrophoretic Methods (Gel Electrophoresis)
- Circular Dichroism
- Cross-Functional Collaboration
- Electrophysiology
- Chromatography
- Dls
- Dsf
- Dsc
- Itc
- Flow Cytometry
- Turbiscanner
- Fluorescence Microscopy
- Critical Quality Attributes (Cqas)
- Nanoluciferase
- Elisa
- Legendplex
- Sop
- Technical And Scientific Presentation
- Cell Culture
- Virus Propagation
- Python
- Molecular Dynamics Simulations
- Drug Screening
- Statistical Analysis
Languages
Education
University Hospital Jena
PhD in Molecular Medicine · Molecular Medicine · Jena, Germany
National Institute of Technology, Rourkela
Integrated Master of Science in Chemistry · Chemistry · Rourkela, India · 7.8/10
Certifications & licenses
Certification In Gmp
Gmp Academy
Project Management
Friedrich Schiller University
Statistics
Experience
Global experience
Expertise
Qualifications
Profile
Frequently asked questions
Have questions? Find more information here.
Sandeep is based in Jena, Germany and can operate in on-site, hybrid, and remote work models.
Sandeep speaks the following languages: English (Advanced), German (Intermediate).
Sandeep has at least 11 years of experience. During this time, Sandeep has worked in at least 6 different roles and for 6 different companies. The average length of individual experience is 2 years and 9 months. Note that Sandeep may not have shared all experience and actually has more experience.
Based on recent experience, Sandeep would be well-suited for roles such as: Postdoctoral Researcher, Scientific Assistant (PhD Scholar), Research Assistant.
Sandeep's most recent position is Postdoctoral Researcher at Friedrich Schiller University.
In recent years, Sandeep has worked for Friedrich Schiller University and University Hospital Jena.
Sandeep is most experienced in industries like Pharmaceutical, Biotechnology, and Healthcare. Sandeep also has some experience in Chemical.
Sandeep is most experienced in business areas like Research and Development, Product Development, and Quality Assurance.
Sandeep has recently worked in industries like Healthcare, Pharmaceutical, and Biotechnology.
Sandeep has recently worked in business areas like Quality Assurance, Research and Development, and Product Development.
Sandeep holds a Doctorate in Molecular Medicine from University Hospital Jena and a Master in Chemistry from National Institute of Technology, Rourkela.
Sandeep has 2 certificates. These include: Certification In Gmp and Project Management.
The availability of Sandeep needs to be confirmed.
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The median daily rate is the middle value of all daily rates — half of comparable freelancers charge less, half charge more. Unlike the average, it is barely affected by outliers.
Calculated based on our freelancers’ daily rates as of 7 Sep 2026. Actual rates may vary depending on seniority level, experience, skill specialization, project complexity, and engagement length.
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